Monday, September 23, 2013

Auto-brewery Syndrome - Free Beer

A personal brewery could fit in there.

A recent 'news' story caught my attention as it was about a man with a bizarre affliction. The subject was apparently drunk to varying degrees for five years straight. Of course this isn't that unusual, except that he was not drinking alcohol, the flora in his gut was fermenting dietary carbohydrates into ethanol. After years of being a suspected 'closet drinker' he was treated with antifungal medication and is now free of his involuntary inebriation.

According to the linked news article the condition is very rare, however upon searching for this syndrome on pubmed I am given a different impression. The only article I found that examined frequency of endogenous ethanol production examined patients blood for a glucose tolerance test. Baseline measurements in 2.7% of patients demonstrated the presence of some ethanol after receiving capsules of glucose. Most surprisingly, over 60% of the patients had an increase in ethanol one hour after receiving oral glucose. Those who had a baseline ethanol measurement also had the greatest increase in blood ethanol levels. Sixty percent is not a rare occurrence and it makes one wonder if endogenous ethanol production is clinically relevant in the context of some health conditions. This has been proposed before but I haven't seen anything convincing.

For context, an 80kg male drinking three drinks in two hours will have a blood ethanol concentration of 33mg/dL, while the measured increases in this study averaged under 3mg/dL and the highest measured increase was 7mg/dL. Clearly, none of the patients would notice the effects of ethanol from dietary carbohydrate ingestion. Additionally, it has already been argued that the possibility of having this syndrome is not a credible defence against a drunk driving charge.

Unfortunately the most 'beneficial' effects of ethanol are achieved, most often, at levels requiring an exogenous source. Fortunately beer is tasty.


Call Girls Kolkata said...

Such a nice blog you have shared here. Thanks for sharing about this with us.
Please visit Call Girls in Kolkata to know why The Call girls in Kolkata are known for their dusky and fair skin tone and you can take the service from any of them according to your wish.

call girls in Kolkata
Kolkata call girls
call girl services in Kolkata
Kolkata call girl services
call girl agency in Kolkata
Kolkata call girls agency
call girl agencies in Kolkata
Kolkata call girl agencies
independent call girls in Kolkata
independent Kolkata call girls
escorts in Kolkata
Kolkata escorts
independent escorts in Kolkata
independent Kolkata escorts

Expert said...

Call Girls in Hyderabad We need genuine people looking Call Girls in Banjara Hills
and Vip single female locanto escorts service in Hyderabad Independent Escort Thank you very much for visiting Delhi NCR. Call Girls in Gurgaon
Call Girls in Banjara Hills

Split Ac Repair in Delhi NCR. Ac Repair Service in Rohini
Fridge, Window Ac, Split Ac Gas Filling service in Delhi All Electronic Machine Repair Samsung, Lg Ac Installation near me
AC Repair Service in Dwarka Delhi

Hitech City Call Girls AC Repair, Led tv repair best technician
lg Led tv repair service center near me LED TV Service Center in Delhi