Showing posts with label telomerase. Show all posts
Showing posts with label telomerase. Show all posts

Wednesday, October 07, 2009

Another Nobel for Non-Coding RNA

By now you have heard that Blackburn, Greider and Szostak have won the Nobel for their work leading to the discovery of telomeres and telomerase - the eukaryotic solution to the end-replication problem. Other than gawking over "THE SECRET OF AGEING" and all the other shit journalists are copying and pasting into each other's newspapers, now would be a good time to take a moment and remember what a badass enzyme telomerase is. A cellular encoded reverse transcriptase, with structural homology to viral RTs, viral RNA polymerases and phage DNA polymerases. That is also composed of an ncRNA component which functions as a sort of a primer.

The molecular secret of ageing could have been something boring like actin. Is it just a coincidence that it's also cool?


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