Friday, July 27, 2007

Reprogramming Mammalian Cell Motility

Wendell Lim's lab continues to lead the way in engineering synthetic cell-signaling pathways (not to mention lab website design). This time it's a Nature paper showing how modular protein-protein interaction domains can be swapped onto Rho guanine nucleotide exchange proteins to rewire morphological signaling pathways to respond to novel inputs.