Friday, July 27, 2007
Reprogramming Mammalian Cell Motility
Wendell Lim's lab continues to lead the way in engineering synthetic cell-signaling pathways (not to mention lab website design). This time it's a Nature paper showing how modular protein-protein interaction domains can be swapped onto Rho guanine nucleotide exchange proteins to rewire morphological signaling pathways to respond to novel inputs.
Posted by Bayman at 12:45 PM 0 comments
Labels: cell motility, gtpase, guanine nucleotide exchange factors, Lim lab, morphology, rho, signaling, synthetic biology
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