The most powerful and beautiful thing I have seen in science happened during my honors project. I had created transgenic zebrafish embryos expressing either GFP or a mutant DNA-methyltransferase fused to GFP (thank you nobel laureates). I then placed the embryos in a groove of agar and followed their development under the GFP scope taking pictures at regular intervals for about 36h. I guess we didn't have time lapse in those days. The great thing about zebrafish is that development is really fast, and the embryo is clear so you can see right through it. At 48h you pretty much have a fully-formed fish. I still remember vividly seeing the cell movements, the formation of the three germ layers, but most impressive I remember seing the heart starting to beat. I fell in love with development. This paper in science brings you this remarkable process in a convenient 1min video. It was done thanks to advances in imaging technology by fully digitizing images from scammed light sheet microscopy and tracking every nucleus of the embryo...
Showing posts with label development. Show all posts
Showing posts with label development. Show all posts
Friday, October 10, 2008
Science video of the day
The most powerful and beautiful thing I have seen in science happened during my honors project. I had created transgenic zebrafish embryos expressing either GFP or a mutant DNA-methyltransferase fused to GFP (thank you nobel laureates). I then placed the embryos in a groove of agar and followed their development under the GFP scope taking pictures at regular intervals for about 36h. I guess we didn't have time lapse in those days. The great thing about zebrafish is that development is really fast, and the embryo is clear so you can see right through it. At 48h you pretty much have a fully-formed fish. I still remember vividly seeing the cell movements, the formation of the three germ layers, but most impressive I remember seing the heart starting to beat. I fell in love with development. This paper in science brings you this remarkable process in a convenient 1min video. It was done thanks to advances in imaging technology by fully digitizing images from scammed light sheet microscopy and tracking every nucleus of the embryo...
Posted by
Anonymous Coward
at
10:03 AM
0
comments
Labels: development, zebrafish
Thursday, May 29, 2008
Chicken Development - Sunny-side up

Check out a series of photos of a chicken developing. The very early ones are especially interesting. Now I know what to look for if I think that my breakfast has been fertilized.
Posted by
Rob
at
7:58 PM
2
comments
Labels: development, eggs
Subscribe to:
Posts (Atom)

Podcast

0 comments:
Post a Comment