Apparently there is a yeast library with every protein C-terminally tagged with GFP. These guys used it to study the expression variation between individual cells. (Nature access required) Interestingly it was environmental response/ stress response genes that showed the most variability. They suggest this is an aquired adaptation so that a genetically homogenous population contains enough variability to adapt to a changing environment.
Thursday, July 20, 2006
Biological Noise
Just another experiment that makes me think all we need to know we could learn from yeast.
Apparently there is a yeast library with every protein C-terminally tagged with GFP. These guys used it to study the expression variation between individual cells. (Nature access required) Interestingly it was environmental response/ stress response genes that showed the most variability. They suggest this is an aquired adaptation so that a genetically homogenous population contains enough variability to adapt to a changing environment.
Apparently there is a yeast library with every protein C-terminally tagged with GFP. These guys used it to study the expression variation between individual cells. (Nature access required) Interestingly it was environmental response/ stress response genes that showed the most variability. They suggest this is an aquired adaptation so that a genetically homogenous population contains enough variability to adapt to a changing environment.
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