Thursday, August 17, 2006

Of Mice and Men bearing tumours

A good article (free access I think) posted on the Nature website focus area on the problems inherent in studing cancer using mouse models. Not a bad read if you've never really thought about some of the more interesting problems. Apparently only 11% of drugs that look good in mice have any effect in humans. The article suggests the only reason we aren't useing the oncomouse is because of patents and that oncomouse would be better than xenografts.