Poor old Mendel's not even around to defend himself...

A landmark paper appearing in Nature, RNA-mediated non-mendelian inheritance of an epigenetic change in the mouse. Like any landmark paper, it raises more questions than it answers, but nonetheless deals another serious blow to almost all facets of the prevalent dogma in molecular genetics. In this spirit, see also:

• Genome-wide non-mendelian inheritance of extra-genomic information in Arabidopsis
• Potent and specific genetic interference by dsRNA in C. elegans
• The elusive gene...