Friday, December 08, 2006

Human Epigenome Progect

Now that the genome is done it's time for HEP. Epigenome I guess refers to the epigenetic information in the genome, which has been shown to differ between different tissues ect, usually this refers to DNA methylation. A paper recently reports the high-resolution methylation profile of a few human chromosomes. I personally didn't get much out of the paper but I really enjoyed the news and views on the paper. Also interesting in the same issue of Nature Genetics there is a paper that demonstrates a relationship between aberrant transciption suppression via histone methylation (another epigenetic expression control mechanism), and bladder cancer.