Tuesday, November 20, 2007
Ethical "Embryonic" Stem Cells from Your Skin
First it was mouse fibroblasts, and now human dermal fibroblasts have been reprogrammed to have pluripotent ES-like potential. Again, as in murine cells, ectopic expression of the fantastic transcription factor foursome of c-myc, Sox4, Klf4, and Oct3/4 will do the trick. Alternatively, Klf4 and c-myc can be substituted with Nanog and Lin28. Either way it's personalized stem cells from your skin. I'm going to get to work on mine right now...
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people visited the bayblab instead of doing their experiments
4 comments:
I'm sorry, did you say totipotency? I though pluripotency was as far as it went.
It's a specific, but there is a difference.
ok, ok you're right. my mistake.
geez. why the fuss about engineered cell culture artifacts anyway?
Technology is about artifacts. Heh.
nice. well put.
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