Tuesday, March 20, 2007
Move over cold FX, the new hotness in questionable approved drugs comes from China. Sibiono Genetech 's drug, Gendicine is based on a replication-deficient adenovirus delivering wt P53. So far it has proven to be quite safe in over 3500 patients, with symptoms resembling the common cold. However we all remember what happened to Jesse Gelsinger. The company claims most patients who have a not too bad prognosis to start with, will show some kind of partial or complete response. Not surprisingly, a lot of foreigners are going to china to get the virus. Are we being unfair to the company only because it originates from China, or is this one of those "stem cell therapy" type shenanigans. This nature news piece weighs in on the issue. In any case China is becoming a major player in the area, and we'll have to get used to the idea of seeing drugs originating there.