Monday, March 26, 2007
While the yeast protein interactome has been exhaustively mapped by a number of research groups using several approaches, the larger and more complex human interactome has yet to be conquered. Taking a step forward in this direction, a group led by University of Ottawa Prof and Ottawa Institute of Systems Biology director Daniel Figeys has published the interactomes of 338 proteins in NPG's Molecular Systems Biology. The set of 6486 interactions between 2371 proteins was mapped using a high-throughput immunoprecipitation/mass spectrometry approach. That's 1% of the human interactome down, 99 more to go!