Aneuploidy Hampers Yeast Cell Proliferation

We recently discussed on the bayblab whether gross chromosomal abnormalities such as aneuploidy, frequently observed in cancer cells, are cause or consequence of tumor formation. A new paper from Torres et al. shows that yeast with extra chromosomes actually grow slower, suggesting that the relationship between aneuploidy and cancer might be a bit more complex (if the phenomenon holds true on human cells). Then again, maybe yeast are just, well...yeast.