The second runner up is John Donoghue, who works on brain/machine interface. Also sexy sexy science. He's working on wireless chips to implant in the brains of paraplegics to allow fine motor control. There has been a lot of progress lately in this field, with artificial retinas etc... A good choice.
The third runner up is Svante Pääbo, who wants to sequence the entire Neanderthal genome. To date, they've only managed 30Mb, still it's no small feat. However it's not the sexiest field, I mean 1999 called and they want their genome project back.
So whatever happened to stem cell biology, the former darling of hot science?